PACSIN2 Antibody, Biotin conjugated

Datasheet
Code CSB-PA890765ED01HU
Size US$299
Uniprot No. Q9UNF0
Protocols ELISA Protocol
Immunogen Recombinant Human Protein kinase C and casein kinase substrate in neurons protein 2 protein (240-410AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II), PACSIN2
Immunogen Species Human
Research Area Signal Transduction
Target Names PACSIN2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Still Have Questions? Leave a Message or Start an on-line Chat
Function Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.
Subcellular Location Cytoplasm, Cytoplasm, cytoskeleton, Cytoplasmic vesicle membrane, Peripheral membrane protein, Cytoplasmic side, Early endosome, Recycling endosome membrane, Cell projection, ruffle membrane, Peripheral membrane protein, Cytoplasmic side, Cell membrane, Peripheral membrane protein, Cytoplasmic side, Cell projection, Membrane, caveola
Protein Families PACSIN family
Tissue Specificity Widely expressed.
Database Links

HGNC: 8571

OMIM: 604960

KEGG: hsa:11252

STRING: 9606.ENSP00000263246

UniGene: Hs.162877

Related Products

PACSIN2 Antibodies

PACSIN2 Antibodies for Homo sapiens (Human)

PACSIN2 Antibodies for Human

PACSIN2 Proteins

PACSIN2 Proteins for Homo sapiens (Human)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.