PANK1 Antibody

Datasheet

Code	CSB-PA017421GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

Q8TE04

Target Names

PANK1

Alternative Names

coaA antibody; hPanK antibody; hPanK1 antibody; PANK antibody; PANK1 antibody; PANK1_HUMAN antibody; PANK1a antibody; PANK1b antibody; PanK1beta antibody; Pantothenate kinase 1 antibody; Pantothenate kinase antibody; Pantothenic acid kinase 1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human PANK1

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis.

Gene References into Functions

p53 plays an important role in regulating energy homeostasis through transcriptional control of PANK1. PMID: 23343762
PANK deficiency leads to abnormalities in F-actin organization. PMID: 22912811
molecular cloning and characterization of a new human PanK gene PMID: 11809413
alternative splicing product PMID: 12379284
PPARalpha transcription factor as a major factor governing hepatic CoA levels by specific modulation of PANK1alpha gene expression PMID: 14523052
analysis of the homodimeric structures of the catalytic cores of PanK1alpha and PanK3 in complex with acetyl-CoA and the the structural effects of the PanK2 mutations that have been implicated in neurodegeneration PMID: 17631502

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Subcellular Location

Cytoplasm.; [Isoform 1]: Nucleus. Nucleus, nucleolus.; [Isoform 2]: Cytoplasm, cytosol. Cytoplasmic vesicle, clathrin-coated vesicle. Recycling endosome.

Protein Families

Type II pantothenate kinase family

Tissue Specificity

[Isoform 1]: Expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis.; [Isoform 2]: Detected at much lower levels in kidney, liver, brain and testis and not detected in heart or skeletal muscle.

Database Links

HGNC: 8598

OMIM: 606160

KEGG: hsa:53354

STRING: 9606.ENSP00000302108

UniGene: Hs.163555

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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