PARD6G Antibody, HRP conjugated

Code CSB-PA863155LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PARD6G Polyclonal antibody
Uniprot No.
Target Names
PARD6G
Alternative Names
PARD6G antibody; PAR6G antibody; Partitioning defective 6 homolog gamma antibody; PAR-6 gamma antibody; PAR6D antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Partitioning defective 6 homolog gamma protein (249-326AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Gene References into Functions
  1. This paper shows Par6G as a negative regulator of the phosphatidylinositol 3'-kinase/phosphoinositide-dependent protein kinase 1/Akt pathway and epithelial cell proliferation and evidence for frequent inactivation of Par6G gene in epithelial cancers. PMID: 26073086
  2. this study is the first to identify Par6gamma as a component of the mother centriole and to report a role of a mother centriole protein in the regulation of centrosomal protein composition. PMID: 23264737
Subcellular Location
Cytoplasm. Cell membrane. Cell junction, tight junction.
Protein Families
PAR6 family
Tissue Specificity
Widely expressed, with a higher expression in fetal and adult kidney.
Database Links

HGNC: 16076

OMIM: 608976

KEGG: hsa:84552

STRING: 9606.ENSP00000343144

UniGene: Hs.654920

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