PEX16 Antibody

Code CSB-PA017801GA01HU
Product Type Purified Rabbit Anti human PolyClonal Antibody
Size US$685
Uniprot No. Q9Y5Y5
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunogen Human PEX16
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications ELISA,WB
Storage Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method Antigen Affinity purified
Isotype IgG
Alias peroxisomal biogenesis factor 16;
Immunogen Species Homo sapiens (Human)
Target Names PEX16
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Details This protein is an integral peroxisomal membrane protein. An inactivating nonsense mutation localized to this gene was observed in a patient with Zellweger syndrome of the complementation group CGD/CG9. Expression of this gene product morphologically and biochemically restores the formation of new peroxisomes, suggesting a role in peroxisome organization and biogenesis. Alternative splicing has been observed for this gene and two variants have been described.
HGNC 8857
RGD 1311372
MGI 1338829
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Function Required for peroxisome membrane biogenesis. May play a role in early stages of peroxisome assembly. Can recruit other peroxisomal proteins, such as PEX3 and PMP34, to de novo peroxisomes derived from the endoplasmic reticulum (ER). May function as receptor for PEX3.
Involvement in disease Peroxisome biogenesis disorder complementation group 9 (PBD-CG9); Peroxisome biogenesis disorder 8A (PBD8A); Peroxisome biogenesis disorder 8B (PBD8B)
Subcellular Location Peroxisome membrane, Multi-pass membrane protein, Endoplasmic reticulum membrane
Protein Families Peroxin-16 family
Database Links

HGNC: 8857

OMIM: 603360

KEGG: hsa:9409

STRING: 9606.ENSP00000241041

UniGene: Hs.100915

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