PIGL Antibody

Code CSB-PA897465LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA897465LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA897465LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PIGL Polyclonal antibody
Uniprot No.
Target Names
PIGL
Alternative Names
N acetylglucosaminylphosphatidylinositol deacetylase antibody; N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase antibody; Phosphatidylinositol glycan anchor biosynthesis class L antibody; Phosphatidylinositol glycan class L antibody; Phosphatidylinositol-glycan biosynthesis class L protein antibody; PIG-L antibody; Pigl antibody; PIGL_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase protein (23-252AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PIGL Antibody (Product code: CSB-PA897465LA01HU) is Non-conjugated. For PIGL Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA897465LB01HU PIGL Antibody, HRP conjugated ELISA
FITC CSB-PA897465LC01HU PIGL Antibody, FITC conjugated
Biotin CSB-PA897465LD01HU PIGL Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.
Gene References into Functions
  1. c.336-2A>G variant in PIGL associated with developmental disorder resulted in exon skipping. PMID: 28327575
  2. these findings indicate that patients with a clinical diagnosis of CHIME syndrome and a single identifiable mutation in PIGL warrant further investigation for copynumber changes involving PMID: 28371479
  3. fd hrhr rt eruj jej PMID: 25706356
  4. Whole-exome sequencing on five previously reported CHIME cases identified PIGL (N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase) as required for glycosylphosphatidylinositol anchor formation. PMID: 22444671
Involvement in disease
Coloboma, congenital heart disease, ichthyosiform dermatosis, mental retardation and ear anomalies syndrome (CHIME)
Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein Families
PIGL family
Database Links

HGNC: 8966

OMIM: 280000

KEGG: hsa:9487

STRING: 9606.ENSP00000225609

UniGene: Hs.499793

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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