PIGT Antibody

Datasheet
Code CSB-PA836170LA01HU
See More Details Free Antibody trial simple
Size US$299
Uniprot No. Q969N2
Image
  • IHC image of CSB-PA836170LA01HU diluted at 1:500 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant Human GPI transamidase component PIG-T protein (402-562AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC; Recommended dilution: IHC:1:500-1:1000
Relevance Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias GPI transamidase component PIG-T (Phosphatidylinositol-glycan biosynthesis class T protein), PIGT
Immunogen Species Homo sapiens (Human)
Research Area Tags & Cell Markers
Target Names PIGT
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates.
Involvement in disease Multiple congenital anomalies-hypotonia-seizures syndrome 3 (MCAHS3); Paroxysmal nocturnal hemoglobinuria 2 (PNH2)
Subcellular Location Endoplasmic reticulum membrane, Single-pass type I membrane protein
Protein Families PIGT family
Database Links

HGNC: 14938

OMIM: 610272

KEGG: hsa:51604

STRING: 9606.ENSP00000279036

UniGene: Hs.437388

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