PKD1L2 Antibody, FITC conjugated

Code CSB-PA773589LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PKD1L2 Polyclonal antibody
Uniprot No.
Target Names
PKD1L2
Alternative Names
PKD1L2 antibody; KIAA1879 antibody; PC1L2 antibody; Polycystic kidney disease protein 1-like 2 antibody; PC1-like 2 protein antibody; Polycystin-1L2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Polycystic kidney disease protein 1-like 2 protein (1-306AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May function as an ion-channel regulator. May function as a G-protein-coupled receptor.
Gene References into Functions
  1. Study found an association between a 6.2 kb dele- tion in the PKD1L2 gene and colorectal cancer in a Korean population. PMID: 27605020
  2. genes are mapped to chromosomes and gene structures are characterized; protein structure is predicted and contains strong ion channel signature motifs that suggest their possible function as components of cation channel pores PMID: 12782129
  3. PKD1L2 is expressed in the developing and adult heart and kidney. PMID: 15203210
  4. Ectopic expression of PKD1L2 in transgenic mice caused severe muscle atrophy. PMID: 19578180
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Polycystin family
Tissue Specificity
Expressed in all tissues tested including brain, placenta, mammary gland, testis, lung and liver. Highest expression in skeletal muscle. Isoform 2 is expressed in heart and kidney.
Database Links

HGNC: 21715

OMIM: 607894

KEGG: hsa:114780

STRING: 9606.ENSP00000469432

UniGene: Hs.413525

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