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PKD1L2 Antibody, FITC conjugated

Datasheet
Code CSB-PA773589LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PKD1L2 Polyclonal antibody
Uniprot No.
Q7Z442
Target Names
PKD1L2
Alternative Names
PKD1L2 antibody; KIAA1879 antibody; PC1L2 antibody; Polycystic kidney disease protein 1-like 2 antibody; PC1-like 2 protein antibody; Polycystin-1L2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Polycystic kidney disease protein 1-like 2 protein (1-306AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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PKD1L2 Antibodies

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Target Background

Function
May function as an ion-channel regulator. May function as a G-protein-coupled receptor.
Gene References into Functions
  1. Study found an association between a 6.2 kb dele- tion in the PKD1L2 gene and colorectal cancer in a Korean population. PMID: 27605020
  2. genes are mapped to chromosomes and gene structures are characterized; protein structure is predicted and contains strong ion channel signature motifs that suggest their possible function as components of cation channel pores PMID: 12782129
  3. PKD1L2 is expressed in the developing and adult heart and kidney. PMID: 15203210
  4. Ectopic expression of PKD1L2 in transgenic mice caused severe muscle atrophy. PMID: 19578180
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Polycystin family
Tissue Specificity
Expressed in all tissues tested including brain, placenta, mammary gland, testis, lung and liver. Highest expression in skeletal muscle. Isoform 2 is expressed in heart and kidney.
Database Links

HGNC: 21715

OMIM: 607894

KEGG: hsa:114780

STRING: 9606.ENSP00000469432

UniGene: Hs.413525

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