PKD1L3 Antibody

Datasheet

Code	CSB-PA767197LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA767197LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA767197LA01HU at dilution of 1:100 Immunofluorescent analysis of A549 cells using CSB-PA767197LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PKD1L3 Polyclonal antibody

Uniprot No.

Q7Z443

Target Names

PKD1L3

Alternative Names

PKD1L3 antibody; Polycystic kidney disease protein 1-like 3 antibody; PC1-like 3 protein antibody; Polycystin-1L3 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Polycystic kidney disease protein 1-like 3 protein (22-194AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The PKD1L3 Antibody (Product code: CSB-PA767197LA01HU) is Non-conjugated. For PKD1L3 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA767197LB01HU	PKD1L3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA767197LC01HU	PKD1L3 Antibody, FITC conjugated
Biotin	CSB-PA767197LD01HU	PKD1L3 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Component of a calcium channel. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect.

Gene References into Functions

our study identified C1 as the first PKD2L1 domain essential for both PKD2L1 trimerization and channel function, and suggest that PKD2L1 and PKD2L1/PKD1L3 channels share the PKD2L1 trimerization process. PMID: 25820328
functions as a channel-forming subunit in an acid-sensing heteromeric complex formed by PKD1L3 and TRPP3 PMID: 23212381
Among the three gustatory regions innervated by peripheral gustatory neurons in the geniculate ganglion, transgenic Pkd1l3 is expressed in the foliate papillae, not in the fungiform papillae or palate. PMID: 21883212
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
the PKD2L1-PKD1L3 complex is involved in acid sensing in vivo PMID: 20406802
genes are mapped to chromosomes and gene structures are characterized; protein structure is predicted and contains strong ion channel signature motifs that suggest their possible function as components of cation channel pores PMID: 12782129

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Subcellular Location

Cell membrane; Multi-pass membrane protein. Note=Interaction with PKD2L1 is required for localization to the cell membrane.

Protein Families

Polycystin family

Tissue Specificity

Highly expressed in placenta, weakly in heart and lung.

Database Links

HGNC: 21716

OMIM: 607895

KEGG: hsa:342372

UniGene: Hs.675286

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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