PKD1L3 Antibody

Code CSB-PA767197LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA767197LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA767197LA01HU at dilution of 1:100

  • Immunofluorescent analysis of A549 cells using CSB-PA767197LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PKD1L3 Polyclonal antibody
Uniprot No.
Target Names
PKD1L3
Alternative Names
PKD1L3 antibody; Polycystic kidney disease protein 1-like 3 antibody; PC1-like 3 protein antibody; Polycystin-1L3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Polycystic kidney disease protein 1-like 3 protein (22-194AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PKD1L3 Antibody (Product code: CSB-PA767197LA01HU) is Non-conjugated. For PKD1L3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA767197LB01HU PKD1L3 Antibody, HRP conjugated ELISA
FITC CSB-PA767197LC01HU PKD1L3 Antibody, FITC conjugated
Biotin CSB-PA767197LD01HU PKD1L3 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of a calcium channel. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect.
Gene References into Functions
  1. our study identified C1 as the first PKD2L1 domain essential for both PKD2L1 trimerization and channel function, and suggest that PKD2L1 and PKD2L1/PKD1L3 channels share the PKD2L1 trimerization process. PMID: 25820328
  2. functions as a channel-forming subunit in an acid-sensing heteromeric complex formed by PKD1L3 and TRPP3 PMID: 23212381
  3. Among the three gustatory regions innervated by peripheral gustatory neurons in the geniculate ganglion, transgenic Pkd1l3 is expressed in the foliate papillae, not in the fungiform papillae or palate. PMID: 21883212
  4. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  5. the PKD2L1-PKD1L3 complex is involved in acid sensing in vivo PMID: 20406802
  6. genes are mapped to chromosomes and gene structures are characterized; protein structure is predicted and contains strong ion channel signature motifs that suggest their possible function as components of cation channel pores PMID: 12782129

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Subcellular Location
Cell membrane; Multi-pass membrane protein. Note=Interaction with PKD2L1 is required for localization to the cell membrane.
Protein Families
Polycystin family
Tissue Specificity
Highly expressed in placenta, weakly in heart and lung.
Database Links

HGNC: 21716

OMIM: 607895

KEGG: hsa:342372

UniGene: Hs.675286

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