PKNOX1 Antibody

1. PREP1 modulates the cellular sensitivity to TGF-beta by inducing the small mothers against decapentaplegic homolog 3 (SMAD3) nuclear translocation. PMID: 25157139
2. High levels of MEIS1 and PREP1, and low levels of PBX4 expression were founded in samples of patients with ALL. PMID: 22185299
3. Single nucleotide polymorphism in gene encoding transcription factor Prep1 is associated with HIV-1-associated dementia PMID: 22347417
4. The tumor suppressor role of Prep1 is associated with the maintenance of genomic stability. PMID: 21715654
5. analysis of the regulatory region of the zebrafish Prep1.1 gene and the promoter of human PREP1 PMID: 21203543
6. Immunohistochemistry on tissue micrroarrays (TMA) generated from three distinct human cohorts comprising a total of some 1000 human tumors revealed that 70% of the tumors express no or extremely low levels of Prep1, unlike normal tissues. PMID: 20106730
7. PKNOX1 gene-dosage imbalance is associated with overexpression of FABP7 in Down syndrome fetal brains. PMID: 12771203
8. PREP-1 has a role in F9 teratocarcinoma cells: it causes an increase of PBX-2 by preventing its degradation PMID: 12871956

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HGNC: 9022

OMIM: 602100

KEGG: hsa:5316

STRING: 9606.ENSP00000291547

UniGene: Hs.431043