PLEKHB2 Antibody

Datasheet

Code	CSB-PA846599LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA846599LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PLEKHB2 Polyclonal antibody

Uniprot No.

Q96CS7

Target Names

PLEKHB2

Alternative Names

Evectin 2 antibody; Evectin-2 antibody; Evectin2 antibody; EVT2 antibody; FLJ20783 antibody; FLJ23679 antibody; FLJ30436 antibody; PH domain containing family B member 2 antibody; PH domain-containing family B member 2 antibody; PKHB2_HUMAN antibody; Pleckstrin homology domain containing family B member 2 antibody; Pleckstrin homology domain containing, family B (evectins) member 2 antibody; Pleckstrin homology domain-containing family B member 2 antibody; Plekhb2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Pleckstrin homology domain-containing family B member 2 protein (1-222AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The PLEKHB2 Antibody (Product code: CSB-PA846599LA01HU) is Non-conjugated. For PLEKHB2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA846599LB01HU	PLEKHB2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA846599LC01HU	PLEKHB2 Antibody, FITC conjugated
Biotin	CSB-PA846599LD01HU	PLEKHB2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Involved in retrograde transport of recycling endosomes.

Gene References into Functions

Knockdown of evectin-2 (a recycling endosome-resident protein) suppresses nuclear localization of YAP and YAP-dependent transcription. Evectin-2 knockdown reduces the ubiquitination and increased the level of Lats1. PMID: 29093443
The crystal structure at 1.75 A resolution of an apo form of human evectin-2 pleckstrin homology domain, in which the ligand-binding site is free from crystal packing and is thus appropriate for comparison with the structure of the complex, is reported. PMID: 22281740
Data show that depletion of evt-2 or masking of intracellular PS suppressed membrane traffic from REs to the Golgi. PMID: 21911378

Subcellular Location

Recycling endosome membrane; Peripheral membrane protein. Note=Specifically detected in tubulovesicular structures, and colocalizes with TFNR.

Database Links

HGNC: 19236

KEGG: hsa:55041

STRING: 9606.ENSP00000385892

UniGene: Hs.469944

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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