PLEKHB2 Antibody

Code CSB-PA846599LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA846599LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PLEKHB2 Polyclonal antibody
Uniprot No.
Target Names
PLEKHB2
Alternative Names
Evectin 2 antibody; Evectin-2 antibody; Evectin2 antibody; EVT2 antibody; FLJ20783 antibody; FLJ23679 antibody; FLJ30436 antibody; PH domain containing family B member 2 antibody; PH domain-containing family B member 2 antibody; PKHB2_HUMAN antibody; Pleckstrin homology domain containing family B member 2 antibody; Pleckstrin homology domain containing, family B (evectins) member 2 antibody; Pleckstrin homology domain-containing family B member 2 antibody; Plekhb2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Pleckstrin homology domain-containing family B member 2 protein (1-222AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PLEKHB2 Antibody (Product code: CSB-PA846599LA01HU) is Non-conjugated. For PLEKHB2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA846599LB01HU PLEKHB2 Antibody, HRP conjugated ELISA
FITC CSB-PA846599LC01HU PLEKHB2 Antibody, FITC conjugated
Biotin CSB-PA846599LD01HU PLEKHB2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in retrograde transport of recycling endosomes.
Gene References into Functions
  1. Knockdown of evectin-2 (a recycling endosome-resident protein) suppresses nuclear localization of YAP and YAP-dependent transcription. Evectin-2 knockdown reduces the ubiquitination and increased the level of Lats1. PMID: 29093443
  2. The crystal structure at 1.75 A resolution of an apo form of human evectin-2 pleckstrin homology domain, in which the ligand-binding site is free from crystal packing and is thus appropriate for comparison with the structure of the complex, is reported. PMID: 22281740
  3. Data show that depletion of evt-2 or masking of intracellular PS suppressed membrane traffic from REs to the Golgi. PMID: 21911378
Subcellular Location
Recycling endosome membrane; Peripheral membrane protein. Note=Specifically detected in tubulovesicular structures, and colocalizes with TFNR.
Database Links

HGNC: 19236

KEGG: hsa:55041

STRING: 9606.ENSP00000385892

UniGene: Hs.469944

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