PPIL2 Antibody

Datasheet

Code	CSB-PA621661ESR1HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA621661ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA621661ESR1HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PPIL2 Polyclonal antibody

Uniprot No.

Q13356

Target Names

PPIL2

Alternative Names

ntibody; CYC4 antibody; Cyclophilin 60 antibody; Cyclophilin 60kDa antibody; Cyclophilin like protein Cyp 60 antibody; Cyclophilin-60 antibody; Cyclophilin-like protein Cyp-60 antibody; CYP60 antibody; hCyP 60 antibody; MGC33174 antibody; MGC787 antibody; Peptidyl prolyl cis trans isomerase like 2 antibody; Peptidyl-prolyl cis-trans isomerase-like 2 antibody; Peptidylprolyl cis trans isomerase antibody; Peptidylprolyl isomerase cyclophilin like 2 antibody; PPIase antibody; PPIL2 antibody; PPIL2_HUMAN antibody; Rotamase antibody; Rotamase PPIL2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Peptidyl-prolyl cis-trans isomerase-like 2 protein (1-260AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Has a ubiquitin-protein ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation. May also function as a chaperone, playing a role in transport to the cell membrane of BSG/Basigin for instance. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.

Gene References into Functions

cyclophilin 60 regulates cell surface expression of CD147/EMMPRIN PMID: 15946952

Subcellular Location

Nucleus.

Protein Families

Cyclophilin-type PPIase family, PPIL2 subfamily

Tissue Specificity

Highest expression in thymus, pancreas and testis. Also detected in heart, placenta, lung, liver, skeletal muscle, kidney, spleen, prostate, ovary, small intestine and colon. Poorly detected in brain and leukocytes. Strong protein expression in lymph node

Database Links

HGNC: 9261

OMIM: 607588

KEGG: hsa:23759

STRING: 9606.ENSP00000390427

UniGene: Hs.438587

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Ubiquitin mediated proteolysis

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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