PPIL2 Antibody

Datasheet

Code	CSB-PA018483GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

Q13356

Target Names

PPIL2

Alternative Names

ntibody; CYC4 antibody; Cyclophilin 60 antibody; Cyclophilin 60kDa antibody; Cyclophilin like protein Cyp 60 antibody; Cyclophilin-60 antibody; Cyclophilin-like protein Cyp-60 antibody; CYP60 antibody; hCyP 60 antibody; MGC33174 antibody; MGC787 antibody; Peptidyl prolyl cis trans isomerase like 2 antibody; Peptidyl-prolyl cis-trans isomerase-like 2 antibody; Peptidylprolyl cis trans isomerase antibody; Peptidylprolyl isomerase cyclophilin like 2 antibody; PPIase antibody; PPIL2 antibody; PPIL2_HUMAN antibody; Rotamase antibody; Rotamase PPIL2 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human PPIL2

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Has a ubiquitin-protein ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation. May also function as a chaperone, playing a role in transport to the cell membrane of BSG/Basigin for instance. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.

Gene References into Functions

cyclophilin 60 regulates cell surface expression of CD147/EMMPRIN PMID: 15946952

Subcellular Location

Nucleus.

Protein Families

Cyclophilin-type PPIase family, PPIL2 subfamily

Tissue Specificity

Highest expression in thymus, pancreas and testis. Also detected in heart, placenta, lung, liver, skeletal muscle, kidney, spleen, prostate, ovary, small intestine and colon. Poorly detected in brain and leukocytes. Strong protein expression in lymph node

Database Links

HGNC: 9261

OMIM: 607588

KEGG: hsa:23759

STRING: 9606.ENSP00000390427

UniGene: Hs.438587

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Ubiquitin mediated proteolysis

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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