PPM1G Antibody

1. PPM1G phosphatase directly binds 7SK RNA and the kinase inhibitor Hexim1 once P-TEFb has been released from the 7SK snRNP. PMID: 26324325
2. Hypermethylation in the 3'-protein-phosphatase-1G (PPM1G) gene locus was associated with alcohol use disorder. PMID: 25982659
3. PPM1G inactivates monomeric WWP2 and promotes the assembly of WWP2-WWP1 heterodimeric complex. PMID: 25071155
4. PPM1G dephosphorylates the P-TEFb kinase T loop to disassemble the 7SK snRNP. PMID: 24316072
5. study has identified protein phosphatase PPM1G as a novel regulator of cap-dependent protein translation by negatively controlling the phosphorylation of 4E-BP1. PMID: 23814053
6. ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage PMID: 22361354
7. The degradation of p21(WAF1/CIP1) induced by PP2Cgamma was mediated in a proteasome-dependent manner. PMID: 17054950
8. Protein phosphatase 2C gamma mediates histone dephosphorylation/exchange in response to DNA damage or checkpoint recovery in higher eukaryotes. PMID: 17074886
9. PP2Cgamma modulates alternative splicing of specific pre-mRNAs coregulated by YB-1. PMID: 17572683
10. an interplay between PPM1G and unrip determine compartment-specific phosphorylation patterns, localization, and function of the SMN complex PMID: 17984321
11. PP2Cgamma is a novel regulator of p21(Cip1/WAF1) protein stability via the Akt signaling pathway. PMID: 19538940
12. Functional study of the mouse homolog PMID: 9271424

Show More

Hide All

HGNC: 9278

OMIM: 605119

KEGG: hsa:5496

STRING: 9606.ENSP00000264714

UniGene: Hs.643951