PPP1R14B Antibody

Code CSB-PA008762
Size US$100
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Product Details

Uniprot No.
Target Names
PPP1R14B
Alternative Names
PHI 1 antibody; PHI1 antibody; Phospholipase C beta 3 neighboring gene protein antibody; Phospholipase C beta 3 neighbouring gene protein antibody; Phospholipase C-beta-3 neighbouring gene protein antibody; PLCB3N antibody; PNG antibody; PP14B_HUMAN antibody; Ppp1r14b antibody; Protein phosphatase 1 regulatory (inhibitor) subunit 14B antibody; Protein phosphatase 1 regulatory subunit 14B antibody; SOM172 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human PHI-1.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
IHC, ELISA
Recommended Dilution
Application Recommended Dilution
IHC 1:100-1:300
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated.
Gene References into Functions
  1. Whereas CPI-17 staining was diffuse, PHI-1 was concentrated along the cell membrane in distinct foci. The common tissue distribution but different cellular localization of PHI-1 and CPI-17 suggest distinctive physiological roles for these PP1 inhibitors. PMID: 15083373
  2. PHI-1 participates in regulatory events at the trailing edge of migrating cells and modulates retraction of endothelial and epithelial cells PMID: 15522888
  3. An inhibitory phosphoprotein that inhibits the myosin- and glycogen-associated holoenzyme versions of protein type-1 phosphatase (PP1) as well as the monomeric catalytic subunit of PP1 in multiple tissues. PMID: 10606530
Subcellular Location
Cytoplasm.
Protein Families
PP1 inhibitor family
Tissue Specificity
Ubiquitous. Expressed at low levels.
Database Links

HGNC: 9057

OMIM: 601140

KEGG: hsa:26472

STRING: 9606.ENSP00000310117

UniGene: Hs.523760

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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