PPP1R16A Antibody

Code CSB-PA922576
Size US$297
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  • Western blot analysis of extracts from Rat heart cells, using PPP1R16A antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PPP1R16A Polyclonal antibody
Uniprot No.
Target Names
PPP1R16A
Alternative Names
2900084E10Rik antibody; Likley ortholog of mouse myosin phosphatase targeting subunit 3 antibody; MGC14333 antibody; Myosin phosphatase target subunit 3 antibody; Myosin phosphatase targeting subunit 3 antibody; Myosin phosphatase-targeting subunit 3 antibody; MYPT3 antibody; PP16A_HUMAN antibody; PPP1R16A antibody; Protein phosphatase 1 regulatory subunit 16A antibody; Protein phosphatase 1, regulatory (inhibitor) subunit 16A antibody; R75527 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human PPP1R16A.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Inhibits protein phosphatase 1 activity toward phosphorylase, myosin light chain and myosin substrates.
Gene References into Functions
  1. PPP1R16A gene expression is decreased in follicular variant of papillary thyroid carcinoma. PMID: 21509594
  2. analysis of a novel mechanism for the phosphorylation of MYPT3 by PKA and activation of the catalytic activity through direct interaction of a central region of MYPT3 with its N-terminal region PMID: 16920702
Subcellular Location
Cell membrane; Lipid-anchor.
Database Links

HGNC: 14941

OMIM: 609172

KEGG: hsa:84988

STRING: 9606.ENSP00000292539

UniGene: Hs.521937

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