PRDM12 Antibody

Code CSB-PA003849
Size US$100
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  • Western Blot analysis of HuvEC cells using PRDM12 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
PRDM12
Alternative Names
PRDM12 antibody; PFM9PR domain zinc finger protein 12 antibody; EC 2.1.1.- antibody; PR domain-containing protein 12 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from the Internal region of Human PRDM12.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in the positive regulation of histone H3-K9 dimethylation.
Gene References into Functions
  1. The natural history of the PRDM12-CIP disorder. PMID: 26975306
  2. PRDM12 and its functional fly homolog Hamlet are evolutionary conserved master regulators of sensory neuronal specification and play a critical role in pain perception PMID: 25891934
  3. Prdm12 is a key factor in the orchestration of sensory neurogenesis. PMID: 26005867
  4. Down-regulation of PRDM12 is associated with the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion PMID: 14523459
Involvement in disease
Neuropathy, hereditary sensory and autonomic, 8 (HSAN8)
Subcellular Location
Nucleus.
Protein Families
Class V-like SAM-binding methyltransferase superfamily
Tissue Specificity
Not found in adult tissues except in dorsal root ganglia.
Database Links

HGNC: 13997

OMIM: 616458

KEGG: hsa:59335

UniGene: Hs.495311

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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