PRKAR1B Antibody

Code CSB-PA783882
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA783882(PRKAR1B Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA783882(PRKAR1B Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
PRKAR1B
Alternative Names
cAMP dependent protein kinase type I beta regulatory subunit antibody; cAMP-dependent protein kinase type I-beta regulatory subunit antibody; KAP1_HUMAN antibody; PKARI beta antibody; PRKAR 1 antibody; PRKAR 1B antibody; PRKAR1 antibody; Prkar1b antibody; PRKAR1B protein antibody; Protein kinase cAMP dependent regulatory type I beta antibody; RIbeta antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide of Human PRKAR1B
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:10000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
Gene References into Functions
  1. No pathogenic PRKAR1B mutations were found in early onset familial dementia patients in a Dutch cohort. PMID: 25108559
  2. This study demonistrated that PRKAR1B mutation associated with a new neurodegenerative disorder with unique pathology. PMID: 24722252
  3. The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status PMID: 11943777
Subcellular Location
Cell membrane.
Protein Families
CAMP-dependent kinase regulatory chain family
Tissue Specificity
Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
Database Links

HGNC: 9390

OMIM: 176911

KEGG: hsa:5575

STRING: 9606.ENSP00000353415

UniGene: Hs.520851

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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