PRKAR1B Antibody

Code CSB-PA783882
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA783882(PRKAR1B Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA783882(PRKAR1B Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
Alternative Names
cAMP dependent protein kinase type I beta regulatory subunit antibody; cAMP-dependent protein kinase type I-beta regulatory subunit antibody; KAP1_HUMAN antibody; PKARI beta antibody; PRKAR 1 antibody; PRKAR 1B antibody; PRKAR1 antibody; Prkar1b antibody; PRKAR1B protein antibody; Protein kinase cAMP dependent regulatory type I beta antibody; RIbeta antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide of Human PRKAR1B
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:10000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
Gene References into Functions
  1. No pathogenic PRKAR1B mutations were found in early onset familial dementia patients in a Dutch cohort. PMID: 25108559
  2. This study demonistrated that PRKAR1B mutation associated with a new neurodegenerative disorder with unique pathology. PMID: 24722252
  3. The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status PMID: 11943777
Subcellular Location
Cell membrane.
Protein Families
CAMP-dependent kinase regulatory chain family
Tissue Specificity
Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
Database Links

HGNC: 9390

OMIM: 176911

KEGG: hsa:5575

STRING: 9606.ENSP00000353415

UniGene: Hs.520851

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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