PRKAR1B Antibody

Datasheet

Code	CSB-PA129156
Size	US$297
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Image	Western blot analysis of extracts from COLO205 cells, using KAP1 antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PRKAR1B Polyclonal antibody

Uniprot No.

P31321

Target Names

PRKAR1B

Alternative Names

cAMP dependent protein kinase type I beta regulatory subunit antibody; cAMP-dependent protein kinase type I-beta regulatory subunit antibody; KAP1_HUMAN antibody; PKARI beta antibody; PRKAR 1 antibody; PRKAR 1B antibody; PRKAR1 antibody; Prkar1b antibody; PRKAR1B protein antibody; Protein kinase cAMP dependent regulatory type I beta antibody; RIbeta antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from internal of Human KAP1.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:3000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.

Gene References into Functions

No pathogenic PRKAR1B mutations were found in early onset familial dementia patients in a Dutch cohort. PMID: 25108559
This study demonistrated that PRKAR1B mutation associated with a new neurodegenerative disorder with unique pathology. PMID: 24722252
The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status PMID: 11943777

Subcellular Location

Cell membrane.

Protein Families

CAMP-dependent kinase regulatory chain family

Tissue Specificity

Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.

Database Links

HGNC: 9390

OMIM: 176911

KEGG: hsa:5575

STRING: 9606.ENSP00000353415

UniGene: Hs.520851

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Insulin signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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