PRLHR Antibody

Code CSB-PA008903
Size US$100
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Product Details

Uniprot No.
Target Names
PRLHR
Alternative Names
PRLHR; GPR10; GR3; Prolactin-releasing peptide receptor; PrRP receptor; PrRPR; G-protein coupled receptor 10; hGR3
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human GPR10.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing.
Gene References into Functions
  1. Effects of systematic N-terminus deletions and benzoylations of endogenous RF-amide peptides on NPFF1R, NPFF2R, GPR10, GPR54 and GPR103. PMID: 26211894
  2. The genotype "A/T" of rs12413624 in PRLHR gene was associated with a decreased risk of colorectal cancer. PMID: 26302849
  3. demonstrate previously unrecognized roles for GPR10 and its upstream regulator REST in the pathogenesis of uterine fibroids PMID: 23284171
  4. structural analysis of the human PrRP receptor (PrRPR) and the ligand-mimicking receptor variant of prolactin-releasing peptide PMID: 22778259
  5. cloning and characterization of the human PrRP receptor gene and its promoter region (PRL-releasing peptide receptor; PrRPR) PMID: 11923475
  6. PrRP receptor has a likely role in pheochromocytomas, based on its high expression in tumor tissue PMID: 12126742
  7. The neuron-restrictive silencer factor confers transcriptional repression of the GPR10 gene via a putative silencer element located in the 5' promoter region. PMID: 12417311
  8. There is an association of polymorphisms in this gene with blood pressure, but not obesity, in a U.K. Caucasian population. PMID: 12716769
  9. A ligand for The rat orphan receptor UHR-1. PMID: 15752583

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Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 1 family
Tissue Specificity
Only detected in the pituitary gland and in all cell types of pituitary adenomas.
Database Links

HGNC: 4464

OMIM: 600895

KEGG: hsa:2834

STRING: 9606.ENSP00000239032

UniGene: Hs.248119

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