PRSS16 Antibody, FITC conjugated

Code CSB-PA882073LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PRSS16 Polyclonal antibody
Uniprot No.
Target Names
PRSS16
Alternative Names
PRSS16 antibody; TSSP antibody; Thymus-specific serine protease antibody; EC 3.4.-.- antibody; Serine protease 16 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Thymus-specific serine protease protein (352-489AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Protease that may play a role in T-cell development.
Gene References into Functions
  1. the level of TSSP expression by thymic dendritic cells may modify the risk factors for multiple sclerosis conferred by some MHC class II haplotypes PMID: 29061767
  2. The genes HIST1H2BJ, PRSS16, and PGBD1 were not associated with Japanese patients with schizophrenia. PMID: 22488895
  3. ZNF804a regulates expression of the schizophrenia-associated genes PRSS16, COMT, PDE4B, and DRD2 PMID: 22384243
  4. The gene encoding thymus-specific serine protease (PRSS16) maps to the extended HLA complex, which harbours several genes predisposing for autoimmune diseases. PMID: 12140752
  5. data suggest that it is unlikely that polymorphisms within the PRSS16 gene are involved in the predisposition to diabetes type 1 PMID: 17584581
  6. our results identify PRSS16 and BTN3A2, two genes thought to play important roles in regulating the immune response, as potentially novel susceptibility genes for Type I diabetes. PMID: 19295542

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Subcellular Location
Cytoplasmic vesicle. Note=Vesicular, either lysosomal or endosomal.
Protein Families
Peptidase S28 family
Tissue Specificity
Expressed predominantly in cortical thymic epithelial cells.
Database Links

HGNC: 9480

OMIM: 607169

KEGG: hsa:10279

STRING: 9606.ENSP00000230582

UniGene: Hs.274407

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