Recombinant Human Thymus-specific serine protease (PRSS16)

Code CSB-YP882073HU
MSDS
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Source Yeast
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Code CSB-EP882073HU
MSDS
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Source E.coli
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Code CSB-EP882073HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP882073HU
MSDS
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Source Baculovirus
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Code CSB-MP882073HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
PRSS16
Uniprot No.
Alternative Names
PRSS16; TSSP; Thymus-specific serine protease; EC 3.4.-.-; Serine protease 16
Species
Homo sapiens (Human)
Expression Region
25-514
Target Protein Sequence
SLLRRL GEHIQQFQES SAQGLGLSLG PGAAALPKVG WLEQLLDPFN VSDRRSFLQR YWVNDQHWVG QDGPIFLHLG GEGSLGPGSV MRGHPAALAP AWGALVISLE HRFYGLSIPA GGLEMAQLRF LSSRLALADV VSARLALSRL FNISSSSPWI CFGGSYAGSL AAWARLKFPH LIFASVASSA PVRAVLDFSE YNDVVSRSLM STAIGGSLEC RAAVSVAFAE VERRLRSGGA AQAALRTELS ACGPLGRAEN QAELLGALQA LVGGVVQYDG QTGAPLSVRQ LCGLLLGGGG NRSHSTPYCG LRRAVQIVLH SLGQKCLSFS RAETVAQLRS TEPQLSGVGD RQWLYQTCTE FGFYVTCENP RCPFSQLPAL PSQLDLCEQV FGLSALSVAQ AVAQTNSYYG GQTPGANKVL FVNGDTDPWH VLSVTQALGS SESTLLIRTG SHCLDMAPER PSDSPSLRLG RQNIFQQLQT WLKLAKESQI KGEV
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Protease that may play a role in T-cell development.
Gene References into Functions
  1. the level of TSSP expression by thymic dendritic cells may modify the risk factors for multiple sclerosis conferred by some MHC class II haplotypes PMID: 29061767
  2. The genes HIST1H2BJ, PRSS16, and PGBD1 were not associated with Japanese patients with schizophrenia. PMID: 22488895
  3. ZNF804a regulates expression of the schizophrenia-associated genes PRSS16, COMT, PDE4B, and DRD2 PMID: 22384243
  4. The gene encoding thymus-specific serine protease (PRSS16) maps to the extended HLA complex, which harbours several genes predisposing for autoimmune diseases. PMID: 12140752
  5. data suggest that it is unlikely that polymorphisms within the PRSS16 gene are involved in the predisposition to diabetes type 1 PMID: 17584581
  6. our results identify PRSS16 and BTN3A2, two genes thought to play important roles in regulating the immune response, as potentially novel susceptibility genes for Type I diabetes. PMID: 19295542

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Subcellular Location
Cytoplasmic vesicle. Note=Vesicular, either lysosomal or endosomal.
Protein Families
Peptidase S28 family
Tissue Specificity
Expressed predominantly in cortical thymic epithelial cells.
Database Links

HGNC: 9480

OMIM: 607169

KEGG: hsa:10279

STRING: 9606.ENSP00000230582

UniGene: Hs.274407

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