PSD Antibody, HRP conjugated

1. Arf GTPases are likely to be locally activated by EFA6 and in turn targeted to the Flemming body to complete cytokinesis. PMID: 26330566
2. PSD expression might be a useful biomarker for epigenetic-based gastric cancer early diagnosis and may lead to the identification of new targets for pharmacological intervention. PMID: 25355626
3. EFA6 is regulated by a negative feedback loop, which is mediated by an allosteric interaction of Arf6-GTP with a domain of EFA6 and monitors the activation of Arf1 and Arf6 differentially PMID: 25114232
4. EFA6 participates in activation of Arf6 around the cleavage furrow during cytokinesis. PMID: 23603394
5. Aberrant methylation of PSD occurs in UC-associated colorectal mucosa, enabling circumvention of Rac1 immune responses governing neutrophil chemotaxis and apoptosis, and plays a pivotal role in the mechanisms underlying UC-associated carcinogenesis. PMID: 22179719
6. Both levels of accumulation of F-actin and apoptosis were significantly decreased in specimens from UC patients with PSD methylation compared to those without PSD methylation. PMID: 22002136
7. Pleckstrin is a critical molecule for proinflammatory cytokine secretion in response to elevated advanced glycation end products (AGE) in diabetes. PMID: 17579087

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HGNC: 9507

OMIM: 602327

KEGG: hsa:5662

STRING: 9606.ENSP00000020673

UniGene: Hs.154658