PSMA5 Antibody

Datasheet

Code	CSB-PA018870LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: A549 whole cell lysate, HepG2 whole cell lysate, Rat liver tissue All lanes: PSMA5 antibody at 3μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 27, 21 kDa Observed band size: 27 kDa Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA018870LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA018870LA01HU at dilution of 1:100
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PSMA5 Polyclonal antibody

Uniprot No.

P28066

Target Names

PSMA5

Alternative Names

Macropain zeta chain antibody; Multicatalytic endopeptidase complex zeta chain antibody; Proteasome (prosome macropain) subunit alpha type 5 antibody; Proteasome alpha5 subunit antibody; Proteasome component 5 antibody; Proteasome subunit alpha type 5 antibody; Proteasome subunit alpha type-5 antibody; Proteasome subunit zeta antibody; Proteasome zeta chain antibody; PSA5_HUMAN antibody; PSC5 antibody; PSMA5 antibody; ZETA antibody

Raised in

Rabbit

Species Reactivity

Human, Rat

Immunogen

Recombinant Human Proteasome subunit alpha type-5 protein (124-180AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The PSMA5 Antibody (Product code: CSB-PA018870LA01HU) is Non-conjugated. For PSMA5 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA018870LB01HU	PSMA5 Antibody, HRP conjugated	ELISA
FITC	CSB-PA018870LC01HU	PSMA5 Antibody, FITC conjugated
Biotin	CSB-PA018870LD01HU	PSMA5 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).

Gene References into Functions

Selective upregulation of the ubiquitin-proteasome proteolytic pathway proteins, proteasome zeta chain and isopeptidase T in fetal Down syndrome. PMID: 11771738

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

Peptidase T1A family

Tissue Specificity

Expressed in fetal brain (at protein level).

Database Links

HGNC: 9534

OMIM: 176844

KEGG: hsa:5686

STRING: 9606.ENSP00000271308

UniGene: Hs.485246

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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