PSMA5 Antibody, HRP conjugated

Datasheet

Code	CSB-PA018870LB01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PSMA5 Polyclonal antibody

Uniprot No.

P28066

Target Names

PSMA5

Alternative Names

Macropain zeta chain antibody; Multicatalytic endopeptidase complex zeta chain antibody; Proteasome (prosome macropain) subunit alpha type 5 antibody; Proteasome alpha5 subunit antibody; Proteasome component 5 antibody; Proteasome subunit alpha type 5 antibody; Proteasome subunit alpha type-5 antibody; Proteasome subunit zeta antibody; Proteasome zeta chain antibody; PSA5_HUMAN antibody; PSC5 antibody; PSMA5 antibody; ZETA antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Proteasome subunit alpha type-5 protein (124-180AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).

Gene References into Functions

Selective upregulation of the ubiquitin-proteasome proteolytic pathway proteins, proteasome zeta chain and isopeptidase T in fetal Down syndrome. PMID: 11771738

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

Peptidase T1A family

Tissue Specificity

Expressed in fetal brain (at protein level).

Database Links

HGNC: 9534

OMIM: 176844

KEGG: hsa:5686

STRING: 9606.ENSP00000271308

UniGene: Hs.485246

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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