PSMB10 Antibody

Datasheet

Code	CSB-PA018877GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

P40306

Target Names

PSMB10

Alternative Names

beta2i antibody; FLJ00366 antibody; LMP10 antibody; Low molecular mass protein 10 antibody; Macropain subunit MECl 1 antibody; Macropain subunit MECl-1 antibody; MECL1 antibody; MGC1665 antibody; Multicatalytic endopeptidase complex subunit MECl 1 antibody; Multicatalytic endopeptidase complex subunit MECl-1 antibody; OTTHUMP00000174858 antibody; Proteasome (prosome macropain) subunit beta type 10 antibody; Proteasome beta 10 subunit antibody; Proteasome catalytic subunit 2i antibody; Proteasome MECl 1 antibody; Proteasome MECl-1 antibody; Proteasome subunit beta 2i antibody; Proteasome subunit beta 7i antibody; Proteasome subunit beta type 10 antibody; Proteasome subunit beta type-10 antibody; Proteasome subunit beta-2i antibody; Proteasome subunit MECL1 antibody; PSB10_HUMAN antibody; PSMB 10 antibody; Psmb10 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human PSMB10

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

Gene References into Functions

this study provided novel evidence demonstrating that LMP10 is a positive regulator of NF-kB signaling, which contributes to Ang II-induced retinopathy. PMID: 29499566
LMP10 nuclear expression in the Human Papillomavirus (HPV)-positive group and LMP10 cytoplasmic expression in the HPV-negative group of patients correlated to better clinical outcome. PMID: 24752327
Adenovirus E1A causes down-regulation of MECL1 expression PMID: 22018786
Multicatalytic endopeptidase complex subunit is involved in antigen presentation and is an important candidate gene for initial exploration of relationships between antigen processing genes and disease resistance. PMID: 17541830

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

Peptidase T1B family

Database Links

HGNC: 9538

OMIM: 176847

KEGG: hsa:5699

STRING: 9606.ENSP00000351314

UniGene: Hs.9661

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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