PSME2 Antibody

Code CSB-PA01134A0Rb
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PSME2 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
11S regulator complex beta subunit antibody; 11S regulator complex subunit beta antibody; Activator of multicatalytic protease subunit 2 antibody; Cell migration inducing protein 22 antibody; MCP activator 31 kD subunit antibody; PA28 beta antibody; PA28b antibody; PA28beta antibody; Proteasome (prosome macropain) activator subunit 2 (PA28 beta) antibody; Proteasome (prosome macropain) activator subunit 2 antibody; Proteasome activator 28 beta antibody; Proteasome activator 28 subunit beta antibody; Proteasome activator complex subunit 2 antibody; Proteasome activator hPA28 subunit beta antibody; Proteasome activator subunit 2 antibody; PSME 2 antibody; PSME2 antibody; PSME2_HUMAN antibody; REG beta antibody; REG-beta antibody; REGbeta antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Proteasome activator complex subunit 2 protein (2-239AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PSME2 Antibody (Product code: CSB-PA01134A0Rb) is Non-conjugated. For PSME2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA01134B0Rb PSME2 Antibody, HRP conjugated ELISA
FITC CSB-PA01134C0Rb PSME2 Antibody, FITC conjugated
Biotin CSB-PA01134D0Rb PSME2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function
Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
Gene References into Functions
  1. The functional assays demonstrate that PA28beta inhibited cell growth, proliferation and malignancy of TE-1 cells. Among the differentially expressed proteins, PA28b is a potential tumor inhibitor PMID: 29020885
  2. Naa10p suppresses 28S proteasome activity through interaction with PA28beta. PMID: 23624078
  3. knockdown of PA28beta could enhance tumor invasion and metastasis, at least in part, through up-regulation of CLIC1 in gastric adenocarcinoma PMID: 22173998
Protein Families
PA28 family
Database Links

HGNC: 9569

OMIM: 602161

KEGG: hsa:5721

STRING: 9606.ENSP00000216802

UniGene: Hs.434081

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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