PTGR2 Antibody

Code CSB-PA018984LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: 293 whole cell lysate, HepG2 whole cell lysate, Hela whole cell lysate
    All lanes: PTGR2 antibody at 3.4µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 39, 20 kDa
    Observed band size: 39 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA018984LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA018984LA01HU at dilution of 1:100

  • Immunofluorescence staining of A549 cells with CSB-PA018984LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PTGR2 Polyclonal antibody
Uniprot No.
Target Names
PTGR2
Alternative Names
15 oxoprostaglandin 13 reductase antibody; 15 oxoprostaglandin delta 13 reductase antibody; 15-oxoprostaglandin 13-reductase antibody; DKFZp686P10120 antibody; FLJ39091 antibody; FLJ99229 antibody; PGR 2 antibody; PGR2 antibody; PRG-2 antibody; Prostaglandin reductase 2 antibody; PTGR 2 antibody; PTGR2 antibody; PTGR2_HUMAN antibody; Zinc binding alcohol dehydrogenase domain containing 1 antibody; Zinc binding alcohol dehydrogenase domain containing protein 1 antibody; Zinc-binding alcohol dehydrogenase domain-containing protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Prostaglandin reductase 2 protein (206-282AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PTGR2 Antibody (Product code: CSB-PA018984LA01HU) is Non-conjugated. For PTGR2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA018984LB01HU PTGR2 Antibody, HRP conjugated ELISA
FITC CSB-PA018984LC01HU PTGR2 Antibody, FITC conjugated
Biotin CSB-PA018984LD01HU PTGR2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.
Gene References into Functions
  1. Silencing of PTGR2 expression enhances reactive oxygen species production, suppresses pancreatic cell proliferation, and promotes cell death through increasing 15-keto-PGE2. PMID: 26820738
  2. Functional data and clinical relevance for the role of PTGR2 in gastric cancer, are provided. PMID: 22998775
  3. Cloning and tissue distribution of a splicing variant ZADH1b. PMID: 15004468
  4. Besides targeting cyclooxygenase, indomethacin inhibits PTGR2 with a binding mode similar to that of 15-keto-PGE(2). PMID: 19000823
Subcellular Location
Cytoplasm.
Protein Families
NADP-dependent oxidoreductase L4BD family
Tissue Specificity
Widely expressed.
Database Links

HGNC: 20149

OMIM: 608642

KEGG: hsa:145482

STRING: 9606.ENSP00000267568

UniGene: Hs.632344

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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