PTGR2 Antibody

Datasheet

Code	CSB-PA234635
Size	US$297
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Image	Western blot analysis of extracts from HUVEC cells, K562 cells and HT-29 cells, using ZADH1 antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PTGR2 Polyclonal antibody

Uniprot No.

Q8N8N7

Target Names

PTGR2

Alternative Names

15 oxoprostaglandin 13 reductase antibody; 15 oxoprostaglandin delta 13 reductase antibody; 15-oxoprostaglandin 13-reductase antibody; DKFZp686P10120 antibody; FLJ39091 antibody; FLJ99229 antibody; PGR 2 antibody; PGR2 antibody; PRG-2 antibody; Prostaglandin reductase 2 antibody; PTGR 2 antibody; PTGR2 antibody; PTGR2_HUMAN antibody; Zinc binding alcohol dehydrogenase domain containing 1 antibody; Zinc binding alcohol dehydrogenase domain containing protein 1 antibody; Zinc-binding alcohol dehydrogenase domain-containing protein 1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from internal of Human ZADH1.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:3000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.

Gene References into Functions

Silencing of PTGR2 expression enhances reactive oxygen species production, suppresses pancreatic cell proliferation, and promotes cell death through increasing 15-keto-PGE2. PMID: 26820738
Functional data and clinical relevance for the role of PTGR2 in gastric cancer, are provided. PMID: 22998775
Cloning and tissue distribution of a splicing variant ZADH1b. PMID: 15004468
Besides targeting cyclooxygenase, indomethacin inhibits PTGR2 with a binding mode similar to that of 15-keto-PGE(2). PMID: 19000823

Subcellular Location

Cytoplasm.

Protein Families

NADP-dependent oxidoreductase L4BD family

Tissue Specificity

Widely expressed.

Database Links

HGNC: 20149

OMIM: 608642

KEGG: hsa:145482

STRING: 9606.ENSP00000267568

UniGene: Hs.632344

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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