PTK7 Antibody, FITC conjugated

Datasheet
Code CSB-PA018996LC01HU
Size US$299
Uniprot No. Q13308
Immunogen Recombinant Human Inactive tyrosine-protein kinase 7 protein (772-1070AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Antigen Affinity Purified
Isotype IgG
Clonality Polyclonal
Alias Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7), PTK7, CCK4
Immunogen Species Human
Protocols ELISA Protocol
Research Area Tags & Cell Markers
Target Names PTK7
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
Subcellular Location Membrane, Single-pass type I membrane protein, Cell junction
Protein Families Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily
Tissue Specificity Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon.
Database Links

HGNC: 9618

OMIM: 601890

KEGG: hsa:5754

STRING: 9606.ENSP00000230419

UniGene: Hs.90572

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