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PTPN18 Antibody

Datasheet
Code CSB-PA858731ESR1HU
Size US$166
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Image
  • Western Blotting(WB) - PTPN18 Antibody

    Western blot
    All lanes: PTPN18 antibody IgG at 2.98μg/ml + Rat heart tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 51, 39 kDa
    Observed band size: 51 kDa

  • Immunohistochemistry(IHC) 1- PTPN18 Antibody

    Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA858731ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PTPN18 Polyclonal antibody
Uniprot No.
Q99952
Target Names
PTPN18
Alternative Names
BDP 1 antibody; Brain derived phosphatase antibody; Brain-derived phosphatase antibody; Protein tyrosine phosphatase non receptor type 18 antibody; Protein tyrosine phosphatase non receptor type 18 brain derived antibody; PTN18_HUMAN antibody; PTP HSCF antibody; PTPN 18 antibody; PTPN18 antibody; Tyrosine protein phosphatase non receptor type 18 antibody; Tyrosine-protein phosphatase non-receptor type 18 antibody
Raised in
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant Human Tyrosine-protein phosphatase non-receptor type 18 protein (1-210AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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PTPN18 Antibodies

PTPN18 Proteins

Customer Reviews and Q&A

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Target Background

Function
Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues.
Gene References into Functions
  1. PTPN12, PTPRN and PTPN18 were independent prognostic factors in Hepatocellular Carcinoma. PMID: 29742497
  2. PTPN18 regulates HER2-mediated cellular functions through defining both its phosphorylation and ubiquitination barcodes. PMID: 25081058
  3. BDP1 has a role in negative regulation of HER2 signaling PMID: 14660651
  4. novel isoform of PTPN18 based on analysis of expressed sequence tags was discovered; deletion of 4 exons in the catalytic domain of the isoform may alter enzymatic activity; 2 of the novel isoform predictions were experimentally validated through RT-PCR PMID: 16303740
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
Protein-tyrosine phosphatase family, Non-receptor class 4 subfamily
Tissue Specificity
Expressed in brain, colon and several tumor-derived cell lines.
Database Links

HGNC: 9649

OMIM: 606587

KEGG: hsa:26469

STRING: 9606.ENSP00000175756

UniGene: Hs.516390

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