PTPN18 Antibody

Code CSB-PA019030GA01HU
Size $600
Order now
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Uniprot No.
Target Names
PTPN18
Alternative Names
BDP 1 antibody; Brain derived phosphatase antibody; Brain-derived phosphatase antibody; Protein tyrosine phosphatase non receptor type 18 antibody; Protein tyrosine phosphatase non receptor type 18 brain derived antibody; PTN18_HUMAN antibody; PTP HSCF antibody; PTPN 18 antibody; PTPN18 antibody; Tyrosine protein phosphatase non receptor type 18 antibody; Tyrosine-protein phosphatase non-receptor type 18 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human PTPN18
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues.
Gene References into Functions
  1. PTPN12, PTPRN and PTPN18 were independent prognostic factors in Hepatocellular Carcinoma. PMID: 29742497
  2. PTPN18 regulates HER2-mediated cellular functions through defining both its phosphorylation and ubiquitination barcodes. PMID: 25081058
  3. BDP1 has a role in negative regulation of HER2 signaling PMID: 14660651
  4. novel isoform of PTPN18 based on analysis of expressed sequence tags was discovered; deletion of 4 exons in the catalytic domain of the isoform may alter enzymatic activity; 2 of the novel isoform predictions were experimentally validated through RT-PCR PMID: 16303740
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
Protein-tyrosine phosphatase family, Non-receptor class 4 subfamily
Tissue Specificity
Expressed in brain, colon and several tumor-derived cell lines.
Database Links

HGNC: 9649

OMIM: 606587

KEGG: hsa:26469

STRING: 9606.ENSP00000175756

UniGene: Hs.516390

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*