PTTG2 Antibody

Datasheet

Code	CSB-PA878936LA01HU
Size	US$166
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Image	Immunofluorescence staining of PC-3 cells with CSB-PA878936LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PTTG2 Polyclonal antibody

Uniprot No.

Q9NZH5

Target Names

PTTG2

Alternative Names

Pituitary tumor transforming 2 antibody; Pituitary tumor transforming gene 2 protein antibody; Pituitary tumor-transforming gene 2 protein antibody; PTTG2 antibody; PTTG2_HUMAN antibody; Securin-2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Securin-2 protein (1-202AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The PTTG2 Antibody (Product code: CSB-PA878936LA01HU) is Non-conjugated. For PTTG2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA878936LB01HU	PTTG2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA878936LC01HU	PTTG2 Antibody, FITC conjugated
Biotin	CSB-PA878936LD01HU	PTTG2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:50-1:200

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Gene References into Functions

PTTG2 induces psoriasis by regulating epidermal expression of vimentin and E-cadherin. PMID: 26617803
Knockdown of PTTG2 results in concomitant downregulation of E-cadherin and elevated vimentin levels, consistent with epithelial-to-mesenchymal transition. PMID: 23470537

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

Securin family

Tissue Specificity

Expressed at low levels in the pituitary, liver, spleen, prostate, testis, ovary, small intestine and colon. Also expressed in various pituitary, testicular, liver and ovarian tumors.

Database Links

HGNC: 9691

OMIM: 604231

KEGG: hsa:10744

STRING: 9606.ENSP00000424261

UniGene: Hs.668806

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Cell cycle

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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