RAB21 Antibody, FITC conjugated

1. Rab21 silencing can induce apoptosis and inhibit proliferation in human glioma cells. PMID: 29270202
2. Starvation-induced MTMR13 and RAB21 activity regulates VAMP8 to promote autophagosome-lysosome fusion. PMID: 25648148
3. High RAB21 expression is associated with glioma. PMID: 24477653
4. Taken together, these data suggest that Rab21 plays a negative role in the EGF-mediated MAPK signaling pathway. Overexpression of Rab21 attenuated EGF-mediated mitogen-activated protein kinase (MAPK) signaling by inducing EGFR degradation. PMID: 22525675
5. Rab21 (and Rab5) associate with the cytoplasmic domains of alpha-integrin chains, and their expression influences the endo/exocytic traffic of integrins. This function of Rab21 is dependent on its GTP/GDP cycle and proper membrane targeting PMID: 16754960
6. Results show that targeted trafficking of integrins to and from the cleavage furrow is required for successful cytokinesis, and that this is regulated by Rab21. PMID: 18804435
7. show that TI-VAMP interacts with the Vps9 domain and ankyrin-repeat-containing protein Varp, a guanine nucleotide exchange factor of the small GTPase Rab21, through a specific domain herein called the interacting domain. PMID: 19745841

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HGNC: 18263

OMIM: 612398

KEGG: hsa:23011

STRING: 9606.ENSP00000261263

UniGene: Hs.524590