RAB3B Antibody, HRP conjugated

Code CSB-PA019195LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RAB3B Polyclonal antibody
Uniprot No.
Target Names
RAB3B
Alternative Names
Brain antigen RAB3B antibody; RAB3B antibody; RAB3B member RAS oncogene family antibody; RAB3B_HUMAN antibody; ras related protein Rab 3B antibody; Ras-related protein Rab-3B antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ras-related protein Rab-3B protein (1-219AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Protein transport. Probably involved in vesicular traffic.
Gene References into Functions
  1. Western blot experiments designed to detect flotillin 2, TMEM256, Rab3B and LAMTOR1 showed that the level of these proteins was higher in urinary exosomes from prostate cancer patients compared to healthy males PMID: 27664330
  2. The structure of Rab3B:GDP complex was solved to 1.9A resolution and the structural base comparison with other Rab3 members provides a structural basis for the GDP/GTP switch in controlling the activity of small GTPase. PMID: 22321395
  3. These results support an important inter-species difference in regulating insulin exocytosis where RAB3B is the most expressed isoform in human islets. PMID: 20807725
  4. RAB3B improves dopamine handling and storage capacity at presynaptic terminals, and confers protection to vulnerable DA neurons. PMID: 20007772
  5. these results add new information to the view that Rab3B is involved in the regulation of pituitary hormone secretion. PMID: 19384079
  6. Rab3b/3c-positive recycling vesicles are involved in and may constitute one of the recycling compartments in exogenous antigen cross-presentation. PMID: 19717423

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Subcellular Location
Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus.
Protein Families
Small GTPase superfamily, Rab family
Database Links

HGNC: 9778

OMIM: 179510

KEGG: hsa:5865

STRING: 9606.ENSP00000360718

UniGene: Hs.123072

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