RAB6B Antibody

Code CSB-PA019217GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
RAB6B
Alternative Names
9630015C03 antibody; AI844641 antibody; C330006L04Rik antibody; D9Bwg0185e antibody; OTTHUMP00000216372 antibody; RAB6B antibody; RAB6B member RAS oncogene family antibody; RAB6B_HUMAN antibody; Ras related protein Rab 6B antibody; Ras-related protein Rab-6B antibody; Small GTP binding protein antibody; Small GTPase RAB6B antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human RAB6B
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.
Gene References into Functions
  1. Conformational changes in human neuronal Rab6B between its inactive GDP and active GTP-like state are observed mainly in the switch I and switch II regions, confirming their role as a molecular switch. PMID: 16790928
  2. The brain-specific Rab6B via Bicaudal-D1 is linked to the dynein/dynactin complex, suggesting a regulatory role for Rab6B in the retrograde transport of cargo in neuronal cells. PMID: 17707369
  3. DYNLRB1 specifically interacts with all three Rab6 isoforms and co-localises at the Golgi. PMID: 18044744
Subcellular Location
Golgi apparatus membrane; Lipid-anchor. Endoplasmic reticulum-Golgi intermediate compartment. Cytoplasmic vesicle.
Protein Families
Small GTPase superfamily, Rab family
Tissue Specificity
Predominantly expressed in brain.
Database Links

HGNC: 14902

OMIM: 615852

KEGG: hsa:51560

STRING: 9606.ENSP00000285208

UniGene: Hs.715344

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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