RAI14 Antibody, HRP conjugated

Code CSB-PA868376LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RAI14 Polyclonal antibody
Uniprot No.
Target Names
RAI14
Alternative Names
Ankycorbin antibody; Ankyrin repeat and coiled coil structure containing protein antibody; Ankyrin repeat and coiled-coil structure-containing protein antibody; DKFZp564G013 antibody; KIAA1334 antibody; NORPEG antibody; Novel retinal pigment epithelial cell protein antibody; RAI13 antibody; RAI14 antibody; RAI14_HUMAN antibody; Retinoic acid induced 14 antibody; Retinoic acid induced protein 14 antibody; Retinoic acid-induced protein 14 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ankycorbin protein (242-346AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in actin regulation at the ectoplasmic specialization, a type of cell junction specific to testis. Important for establishment of sperm polarity and normal spermatid adhesion. May also promote integrity of Sertoli cell tight junctions at the blood-testis barrier.
Gene References into Functions
  1. TCGA database and Kaplan-Meier Plotter mining results showed that compared to those with RAI14 low mRNA expression levels, Gastric Cancer patients with RAI14 high mRNA expression levels had remarkably lower time of both overall survival and disease-free survival. Cox multivariate survival analyses shows high expression of RAI14 was the only independent predictor of unfavorable prognosis in patients with gastric cancer. PMID: 29654694
  2. Subcellular localization of NORPEG in retinal pigment epithelial (ARPE-19) cells varies with cell density, with predominantly nuclear localization in nonconfluent cells, but a cytoplasmic localization in confluent cultures. PMID: 16729964
Subcellular Location
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, cell cortex. Cell junction. Nucleus.
Tissue Specificity
Highly expressed in placenta, muscle, kidney and testis. Moderately expressed in heart, brain, lung, liver and intestine. Isoform 2 is widely expressed and expressed in fetal and adult testes, and spermatozoa.
Database Links

HGNC: 14873

OMIM: 606586

KEGG: hsa:26064

STRING: 9606.ENSP00000427123

UniGene: Hs.431400

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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