RARS2 Antibody

Datasheet

Code	CSB-PA732918ESR2HU
Size	US$166
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Image	Western blot All lanes: RARS2 antibody at 2.68 μg/ml Lane 1: Mouse kidney tissue Lane 2: HL60 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 66 kDa Observed band size: 66 kDa Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA732918ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA732918ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) RARS2 Polyclonal antibody

Uniprot No.

Q5T160

Target Names

RARS2

Alternative Names

arginine tRNA ligase antibody; arginyl tRNA synthetase 2 mitochondrial antibody; Arginyl tRNA synthetase antibody; Arginyl-tRNA synthetase antibody; ArgRS antibody; DALRD2 antibody; mitochondrial antibody; PCH6 antibody; Probable arginine tRNA ligase antibody; probable arginine tRNA ligase mitochondrial antibody; Probable arginine--tRNA ligase antibody; probable arginyl tRNA synthetase mitochondrial antibody; RARS2 antibody; RARSL antibody; SYRM_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Probable arginine--tRNA ligase, mitochondrial protein (17-340AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Gene References into Functions

Characteristic neuroradiological abnormalities of PCH6 such as vermis and cerebellar hypoplasia and progressive pontocerebellar atrophy may be missing in patients with RARS2 mutations PMID: 27769281
RARS2 gene mutations can cause a metabolic neurodegenerative disease manifesting primarily as early onset epileptic encephalopathies with post-natal microcephaly, without pontocerebellar hypoplasia. PMID: 26970947
Mutations in the RARS2 promoter are likely to represent a new causal mechanism of pontocerebellar hypoplasia. PMID: 25809939
Molecular investigations of RARS2 disclosed the c.25A>G/p.I9V and the c.1586+3A>T in family A. PMID: 22569581
mutations in the gene encoding mitochondrial arginyl-tRNA synthetase, RARS2, may have a role in pontocerebellar hypoplasia type 6 [case report] PMID: 22086604

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Involvement in disease

Pontocerebellar hypoplasia 6 (PCH6)

Subcellular Location

Mitochondrion matrix.

Protein Families

Class-I aminoacyl-tRNA synthetase family

Database Links

HGNC: 21406

OMIM: 611523

KEGG: hsa:57038

STRING: 9606.ENSP00000358549

UniGene: Hs.485910

Promotions

Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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