RCAN2 Antibody

Code CSB-PA019501GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
RCAN2
Alternative Names
Calcipressin 2 antibody; Calcipressin-2 antibody; CSP2 antibody; Down syndrome candidate region 1-like 1 antibody; Down syndrome critical region gene 1 like 1 protein antibody; DSCR1L1 antibody; MCIP2 antibody; Myocyte enriched calcineurin interacting protein 2 antibody; Myocyte-enriched calcineurin-interacting protein 2 antibody; RCAN2 antibody; RCAN2_HUMAN antibody; RCN2 antibody; Regulator of calcineurin 2 antibody; Thyroid hormone responsive gene ZAKI4 antibody; Thyroid hormone responsive protein ZAKI4 antibody; thyroid hormone-responsive (skin fibroblasts) antibody; Thyroid hormone-responsive protein ZAKI-4 antibody; ZAKI4 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human RCAN2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
Gene References into Functions
  1. RCAN2 expression is upregulated in human masticatory mucosa during wound healing PMID: 28005267
  2. our data have elucidated the molecular and cellular mechanism whereby PGF(2alpha) regulates CXCL8 expression via the FP receptor in endometrial adenocarcinomas and have highlighted RCAN1-4 as a negative regulator of CXCL8 expression PMID: 19819266
  3. the expression of ZAKI-4 isoforms is subjected to distinct hormonal as well as tissue-specific regulation, constituting a complex signalling network through inhibition of calcineurin. PMID: 12102656
  4. DSCR1-L1 is constitutively expressed in endothelial cells and acts similar to DSCR1 in inhibiting calcineurin activity and restraining VEGF-mediated angiogenesis. PMID: 17610901
Protein Families
RCAN family
Tissue Specificity
Expressed in fibroblasts, heart, brain, liver, and skeletal muscle but not in placenta, lung, kidney and pancreas.
Database Links

HGNC: 3041

OMIM: 604876

KEGG: hsa:10231

STRING: 9606.ENSP00000329454

UniGene: Hs.440168

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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