RCAN2 Antibody

Code CSB-PA239101
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA239101(RCAN2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
RCAN2
Alternative Names
Calcipressin 2 antibody; Calcipressin-2 antibody; CSP2 antibody; Down syndrome candidate region 1-like 1 antibody; Down syndrome critical region gene 1 like 1 protein antibody; DSCR1L1 antibody; MCIP2 antibody; Myocyte enriched calcineurin interacting protein 2 antibody; Myocyte-enriched calcineurin-interacting protein 2 antibody; RCAN2 antibody; RCAN2_HUMAN antibody; RCN2 antibody; Regulator of calcineurin 2 antibody; Thyroid hormone responsive gene ZAKI4 antibody; Thyroid hormone responsive protein ZAKI4 antibody; thyroid hormone-responsive (skin fibroblasts) antibody; Thyroid hormone-responsive protein ZAKI-4 antibody; ZAKI4 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide of Human RCAN2
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
Gene References into Functions
  1. RCAN2 expression is upregulated in human masticatory mucosa during wound healing PMID: 28005267
  2. our data have elucidated the molecular and cellular mechanism whereby PGF(2alpha) regulates CXCL8 expression via the FP receptor in endometrial adenocarcinomas and have highlighted RCAN1-4 as a negative regulator of CXCL8 expression PMID: 19819266
  3. the expression of ZAKI-4 isoforms is subjected to distinct hormonal as well as tissue-specific regulation, constituting a complex signalling network through inhibition of calcineurin. PMID: 12102656
  4. DSCR1-L1 is constitutively expressed in endothelial cells and acts similar to DSCR1 in inhibiting calcineurin activity and restraining VEGF-mediated angiogenesis. PMID: 17610901
Protein Families
RCAN family
Tissue Specificity
Expressed in fibroblasts, heart, brain, liver, and skeletal muscle but not in placenta, lung, kidney and pancreas.
Database Links

HGNC: 3041

OMIM: 604876

KEGG: hsa:10231

STRING: 9606.ENSP00000329454

UniGene: Hs.440168

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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