RERG Antibody

Code CSB-PA850254LA01HU
Size US$166
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  • Western blot
    All lanes: RERG antibody at 2μg/ml
    Lane 1: Mouse thymus tissue
    Lane 2: Rat lung tissue
    Secondary
    Goat polyclonal to rabbit at 1/10000 dilution
    Predicted band size: 23, 21 kDa
    Observed band size: 23 kDa

  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA850254LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA850254LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA850254LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RERG Polyclonal antibody
Uniprot No.
Target Names
RERG
Alternative Names
MGC15754 antibody; RAS like estrogen regulated growth inhibitor antibody; Ras related and estrogen regulated growth inhibitor antibody; Ras-related and estrogen-regulated growth inhibitor antibody; Rerg antibody; RERG_HUMAN antibody; Weakly similar to N ras protein [H.sapiens] antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Human Ras-related and estrogen-regulated growth inhibitor protein (1-199AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The RERG Antibody (Product code: CSB-PA850254LA01HU) is Non-conjugated. For RERG Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA850254LB01HU RERG Antibody, HRP conjugated ELISA
FITC CSB-PA850254LC01HU RERG Antibody, FITC conjugated
Biotin CSB-PA850254LD01HU RERG Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.
Gene References into Functions
  1. this study shows that miR-382-5p expression is negatively correlated with RERG expression, and functions as an independent oncomiR for the higher incidence and poorer prognosis of breast cancer PMID: 27705918
  2. Estradiol estrogen receptor-beta and PGE2 integrate at RERG, leading to increased endometriotic cell proliferation. PMID: 24992181
  3. Results describe the mRNA expression of CRABP1, RERG, and GRP in pituitary adenomas. PMID: 21270509
  4. Loss of RERG expression is associated with breast cancer and distant metastasis. PMID: 20697807
Subcellular Location
Cytoplasm.
Protein Families
Small GTPase superfamily, Ras family
Tissue Specificity
Detected in heart, brain, placenta, lung, liver, skin, kidney and pancreas. Detected in estrogen receptor-positive breast-derived cell lines, but not in estrogen receptor-negative cell lines. Expression is decreased or lost in a significant proportion of
Database Links

HGNC: 15980

OMIM: 612664

KEGG: hsa:85004

STRING: 9606.ENSP00000256953

UniGene: Hs.199487

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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