RERG Antibody

Code CSB-PA850254LA01HU
Size US$166
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  • Western blot
    All lanes: RERG antibody at 2μg/ml
    Lane 1: Mouse thymus tissue
    Lane 2: Rat lung tissue
    Secondary
    Goat polyclonal to rabbit at 1/10000 dilution
    Predicted band size: 23, 21 kDa
    Observed band size: 23 kDa

  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA850254LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA850254LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA850254LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RERG Polyclonal antibody
Uniprot No.
Target Names
RERG
Alternative Names
MGC15754 antibody; RAS like estrogen regulated growth inhibitor antibody; Ras related and estrogen regulated growth inhibitor antibody; Ras-related and estrogen-regulated growth inhibitor antibody; Rerg antibody; RERG_HUMAN antibody; Weakly similar to N ras protein [H.sapiens] antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Human Ras-related and estrogen-regulated growth inhibitor protein (1-199AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The RERG Antibody (Product code: CSB-PA850254LA01HU) is Non-conjugated. For RERG Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA850254LB01HU RERG Antibody, HRP conjugated ELISA
FITC CSB-PA850254LC01HU RERG Antibody, FITC conjugated
Biotin CSB-PA850254LD01HU RERG Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.
Gene References into Functions
  1. this study shows that miR-382-5p expression is negatively correlated with RERG expression, and functions as an independent oncomiR for the higher incidence and poorer prognosis of breast cancer PMID: 27705918
  2. Estradiol estrogen receptor-beta and PGE2 integrate at RERG, leading to increased endometriotic cell proliferation. PMID: 24992181
  3. Results describe the mRNA expression of CRABP1, RERG, and GRP in pituitary adenomas. PMID: 21270509
  4. Loss of RERG expression is associated with breast cancer and distant metastasis. PMID: 20697807
Subcellular Location
Cytoplasm.
Protein Families
Small GTPase superfamily, Ras family
Tissue Specificity
Detected in heart, brain, placenta, lung, liver, skin, kidney and pancreas. Detected in estrogen receptor-positive breast-derived cell lines, but not in estrogen receptor-negative cell lines. Expression is decreased or lost in a significant proportion of
Database Links

HGNC: 15980

OMIM: 612664

KEGG: hsa:85004

STRING: 9606.ENSP00000256953

UniGene: Hs.199487

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