RFPL3 Antibody

Code CSB-PA019600LA01HU
Size US$166
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  • Western blot
    All lanes: RFPL3 antibody at 8µg/ml
    Lane 1: Human placenta tissue
    Lane 2: HL60 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 36, 33 kDa
    Observed band size: 36 kDa
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RFPL3 Polyclonal antibody
Uniprot No.
Target Names
RFPL3
Alternative Names
RFPL3 antibody; Ret finger protein-like 3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ret finger protein-like 3 protein (8-288AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The RFPL3 Antibody (Product code: CSB-PA019600LA01HU) is Non-conjugated. For RFPL3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA019600LB01HU RFPL3 Antibody, HRP conjugated ELISA
FITC CSB-PA019600LC01HU RFPL3 Antibody, FITC conjugated
Biotin CSB-PA019600LD01HU RFPL3 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
(Microbial infection) Stimulates the activity of Human Immunodeficiency Virus 1/HIV-1 pre-integration complex.
Gene References into Functions
  1. EGF significantly upregulated RFPL3 and hTERT protein levels in the nonsmall cell lung cancer cells. RFPL3 and hTERT proteins upregulation by EGF were attenuated by pretreatment with AG1478 and erlotinib. EGF promoted proliferation and inhibited apoptosis; PD98059 decreased RFPL3 and hTERT protein expression; and RFPL3 overexpression increased the expression of hTERT and related MEKpathway proteins PMID: 29749533
  2. RFPL3 and CBP have roles in upregulating hTERT activity and promoting lung cancer growth PMID: 26318425
  3. These results demonstrate that RFPL3 is an important cellular factor which promotes lung cancer growth by activating hTERT expression PMID: 25481043
  4. RFPL3 is a potential stimulator of human immunodeficiency virus, type 1 (HIV-1) preintegration complex integration. PMID: 25107902
  5. the human RFPL1,2,3 genes have a role in neocortex development PMID: 18656177

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Subcellular Location
Cytoplasm. Nucleus.
Tissue Specificity
Expressed during neurogenesis in differentiating human embryonic stem cells and in the developing human neocortex.
Database Links

HGNC: 9980

OMIM: 605970

KEGG: hsa:10738

STRING: 9606.ENSP00000249007

UniGene: Hs.558455

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