RGL2 Antibody

Datasheet

Code	CSB-PA019625LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: Hela whole cell lysate, K562 whole cell lysate, Mouse heart tissue, Rat liver tissue All lanes: RGL2 antibody at 3.2μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 84, 51 kDa Observed band size: 84 kDa Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA019625LA01HU at dilution of 1:100 Immunofluorescent analysis of Hela cells using CSB-PA019625LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) RGL2 Polyclonal antibody

Uniprot No.

O15211

Target Names

RGL2

Alternative Names

GDS related protein antibody; HKE1.5 antibody; KE1.5 antibody; RAB2L antibody; Ral guanine nucleotide dissociation stimulator-like 2 antibody; RalGDS-like 2 antibody; RalGDS-like factor antibody; Ras-associated protein RAB2L antibody; RGL2 antibody; RGL2_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Human Ral guanine nucleotide dissociation stimulator-like 2 protein (145-328AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The RGL2 Antibody (Product code: CSB-PA019625LA01HU) is Non-conjugated. For RGL2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA019625LB01HU	RGL2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA019625LC01HU	RGL2 Antibody, FITC conjugated
Biotin	CSB-PA019625LD01HU	RGL2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro.

Gene References into Functions

SAMD9, an IFN-gamma-responsive protein, interacts with RGL2 to diminish the expression of EGR1, a protein of direct relevance to the pathogenesis of ectopic calcification and inflammation. PMID: 21160498
Rgl2 and RalB both localized to the leading edge, and this localization of RalB was dependent on endogenous Rgl2 expression. PMID: 20801877
RGL2 is phosphorylated by PKA and phosphorylation reduces the ability of RGL2 to bind H-Ras. results of the present study indicate that Ras may distinguish between the different RalGDS family members by their phosphorylation by PKA. PMID: 18540861

Database Links

HGNC: 9769

OMIM: 602306

KEGG: hsa:5863

STRING: 9606.ENSP00000420211

UniGene: Hs.509622

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Ras signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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