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RGL2 Antibody, HRP conjugated

Datasheet
Code CSB-PA019625LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RGL2 Polyclonal antibody
Uniprot No.
O15211
Target Names
RGL2
Alternative Names
GDS related protein antibody; HKE1.5 antibody; KE1.5 antibody; RAB2L antibody; Ral guanine nucleotide dissociation stimulator-like 2 antibody; RalGDS-like 2 antibody; RalGDS-like factor antibody; Ras-associated protein RAB2L antibody; RGL2 antibody; RGL2_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ral guanine nucleotide dissociation stimulator-like 2 protein (145-328AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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RGL2 Antibodies

RGL2 Proteins

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Target Background

Function
Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro.
Gene References into Functions
  1. SAMD9, an IFN-gamma-responsive protein, interacts with RGL2 to diminish the expression of EGR1, a protein of direct relevance to the pathogenesis of ectopic calcification and inflammation. PMID: 21160498
  2. Rgl2 and RalB both localized to the leading edge, and this localization of RalB was dependent on endogenous Rgl2 expression. PMID: 20801877
  3. RGL2 is phosphorylated by PKA and phosphorylation reduces the ability of RGL2 to bind H-Ras. results of the present study indicate that Ras may distinguish between the different RalGDS family members by their phosphorylation by PKA. PMID: 18540861
Database Links

HGNC: 9769

OMIM: 602306

KEGG: hsa:5863

STRING: 9606.ENSP00000420211

UniGene: Hs.509622

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Related pathways
Ras signaling pathway
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