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RGS13 Antibody

Datasheet
Code CSB-PA019645GA01HU
Size $600
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Product Details

Uniprot No.
O14921
Target Names
RGS13
Alternative Names
AL713991.1 antibody; HGNC:9995 antibody; MGC17173 antibody; OTTMUSP00000022853 antibody; OTTMUSP00000022854 antibody; Regulator of G protein signalling 13 antibody; Regulator of G-protein signaling 13 antibody; RGD1562103 antibody; RGS 13 antibody; RGS13 antibody; RGS13_HUMAN antibody; RP11 92K2.1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human RGS13
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,IHC
Protocols
ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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RGS13 Proteins

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Target Background

Function
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to both G(i)-alpha and G(q)-alpha.
Gene References into Functions
  1. p53 may modulate immune responses through suppression of RGS13 transcription in mast cells and B cells PMID: 21531726
  2. RGS13 turnover was significantly reduced in cells stimulated with cAMP, which was reversed by expression of the PKA-specific inhibitory peptide PKI. PMID: 20974683
  3. Functional characterization of the G protein regulator RGS13 PMID: 11875076
  4. Down-Regulation of regulator of G-protein signalling 13 is associated with mantle cell lymphoma PMID: 12970790
  5. RGS13 overexpression inhibited CXCL12-evoked Ca(2+) mobilization, Akt phosphorylation and chemotaxis. PMID: 19017978

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Database Links

HGNC: 9995

OMIM: 607190

KEGG: hsa:6003

STRING: 9606.ENSP00000375853

UniGene: Hs.497220

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