RHOQ Antibody

1. Exocytosis of Rab11- and L1-positive vesicles may play a central role in TC10-mediated neurite outgrowth PMID: 24223996
2. Novel tumor-associated increase of RNA editing in ras homologue family member Q (RHOQ) transcripts, is reported. PMID: 24663214
3. The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin PMID: 12687004
4. Overexpression of the Rho family member TC10alpha, disrupts adipocyte cortical actin structure and inhibits insulin-stimulated GLUT4 translocation PMID: 12972548
5. The GTP-bound form of TC10 directs the trafficking of CFTR from the juxtanuclear region to the secretory pathway toward the plasma membrane PMID: 15546864
6. The crystal structure of TC10 proved that the basic region of WASp and two unique glutamates in Cdc42 generate favorable electrostatic steering forces that control the accelerated WASp-Cdc42 association reaction. PMID: 16246732
7. We propose that an EGF-stimulated GAP accelerates GTP hydrolysis of TC10, thereby promoting vesicle fusion. PMID: 16950130
8. These findings reveal a novel signaling pathway in human skeletal muscle that involves obscurin and the Rho GTPase TC10 and implicate this pathway in new sarcomere formation. PMID: 19258391

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HGNC: 17736

OMIM: 605857

KEGG: hsa:23433

STRING: 9606.ENSP00000238738

UniGene: Hs.709193