RNASEH2C Antibody

Datasheet

Code	CSB-PA837441LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: HEK293 whole cell lysate, Hela whole cell lysate All lanes: RNASEH2C antibody at 3μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 18 kDa Observed band size: 18 kDa Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA837441LA01HU at dilution of 1:100 Immunofluorescent analysis of Hela cells using CSB-PA837441LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) RNASEH2C Polyclonal antibody

Uniprot No.

Q8TDP1

Target Names

RNASEH2C

Alternative Names

RNASEH2C antibody; AYP1 antibody; Ribonuclease H2 subunit C antibody; RNase H2 subunit C antibody; Aicardi-Goutieres syndrome 3 protein antibody; AGS3 antibody; RNase H1 small subunit antibody; Ribonuclease HI subunit C antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Ribonuclease H2 subunit C protein (1-164AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The RNASEH2C Antibody (Product code: CSB-PA837441LA01HU) is Non-conjugated. For RNASEH2C Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA837441LB01HU	RNASEH2C Antibody, HRP conjugated	ELISA
FITC	CSB-PA837441LC01HU	RNASEH2C Antibody, FITC conjugated
Biotin	CSB-PA837441LD01HU	RNASEH2C Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.

Gene References into Functions

This study reviewed that Neurologic Phenotypes Associated with Mutations in RNASEH2C in patients with Aicardi-Goutieres Syndrome. PMID: 27643693
Examination of the effect of several Aicardi-Goutieres Syndrome-related mutations in the C subunit of RNase H2. PMID: 19015152
Describes an RNASEH2C pseudogene that is located close to the SRY gene on chromosome Y. PMID: 8244390

Involvement in disease

Aicardi-Goutieres syndrome 3 (AGS3)

Subcellular Location

Nucleus.

Protein Families

RNase H2 subunit C family

Tissue Specificity

Widely expressed.

Database Links

HGNC: 24116

OMIM: 610329

KEGG: hsa:84153

STRING: 9606.ENSP00000308193

UniGene: Hs.718438

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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