RNF220 Antibody, FITC conjugated

Datasheet
Code CSB-PA719619LC01HU
Size US$299
Uniprot No. Q5VTB9
Protocols ELISA Protocol
Immunogen Recombinant Human E3 ubiquitin-protein ligase RNF220 protein (384-472AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658).
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias E3 ubiquitin-protein ligase RNF220 (EC 2.3.2.27) (RING finger protein 220) (RING-type E3 ubiquitin transferase RNF220), RNF220, C1orf164
Immunogen Species Homo sapiens (Human)
Research Area Epigenetics and Nuclear Signaling
Target Names RNF220
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling
Subcellular Location Cytoplasm
Database Links

HGNC: 25552

OMIM: 616136

KEGG: hsa:55182

STRING: 9606.ENSP00000347548

UniGene: Hs.456557

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