RNF26 Antibody

Datasheet

Code	CSB-PA019883LA01HU
Size	US$166
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Image	Western blot All lanes: RNF26 antibody at 6µg/ml + 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 48 kDa Observed band size: 48 kDa Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA019883LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA019883LA01HU at dilution of 1:100 Immunofluorescent analysis of HepG2 cells using CSB-PA019883LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) RNF26 Polyclonal antibody

Uniprot No.

Q9BY78

Target Names

RNF26

Alternative Names

RNF26; E3 ubiquitin-protein ligase RNF26; RING finger protein 26

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human E3 ubiquitin-protein ligase RNF26 protein (246-433AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The RNF26 Antibody (Product code: CSB-PA019883LA01HU) is Non-conjugated. For RNF26 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA019883LB01HU	RNF26 Antibody, HRP conjugated	ELISA
FITC	CSB-PA019883LC01HU	RNF26 Antibody, FITC conjugated
Biotin	CSB-PA019883LD01HU	RNF26 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

E3 ubiquitin-protein ligase that plays a key role in endosome organization by retaining vesicles in the perinuclear cloud. Acts as a platform for perinuclear positioning of the endosomal system by mediating ubiquitination of SQSTM1. Ubiquitinated SQSTM1 attracts specific vesicle-associated adapters, forming a molecular bridge that restrains cognate vesicles in the perinuclear region and organizes the endosomal pathway for efficient cargo transport. Also acts as a regulator of type I interferon production in response to viral infection by mediating the formation of 'Lys-11'-linked polyubiquitin chains on TMEM173/STING, leading to stabilize TMEM173/STING. Also required to limit type I interferon response by promoting autophagic degradation of IRF3.

Gene References into Functions

Study reveals the endoplasmic reticulum (ER)-located ubiquitin ligase Ring finger protein 26 (RNF26) as the global architect of the entire endosomal system, including the trans-Golgi network. PMID: 27368102

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Tissue Specificity

Ubiquitous. Up-regulated in several cancer cell lines.

Database Links

HGNC: 14646

OMIM: 606130

KEGG: hsa:79102

UniGene: Hs.524084

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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