ROS1 Antibody

1. ound that DOGL4 negatively affects seed dormancy and response to the phytohormone abscisic acid and that ROS1 controls these processes by regulating DOGL4 PMID: 30266793
2. Results provide evidence that ROS1 expression is regulated by MET18 which is required for its activity. ROS1 binds to the iron-sulfur cluster of MET18. PMID: 27193999
3. ROS1 preferentially targets transposable elements (TEs) and intergenic regions. Compared with most TEs, ROS1-targeted TEs are closer to protein coding genes, suggesting that ROS1 may prevent DNA methylation spreading from TEs to nearby genes. PMID: 27797352
4. Transgenic tobacco overexpressing AtROS1 showed tolerance to salt stress that could have been due to the higher expression levels of the genes encoding enzymes of the flavonoid biosynthetic and antioxidant pathways. PMID: 26116024
5. Our results suggest that ROS1-mediated active DNA demethylation requires MET18-dependent transfer of the iron-sulfur cluster, highlighting an important role of the CIA pathway in epigenetic regulation. PMID: 26492035
6. We propose that the ROS1 locus functions as an epigenetic rheostat, tuning the level of demethylase activity in response to methylation alterations, thus ensuring epigenomic stability. PMID: 25826366
7. ROS1, DML2, and DML3 play a role in fungal disease resistance in Arabidopsis PMID: 25228471
8. ROS1 mediated DNA demethylation combats the activity of RNA-directed DNA methylation to influence the initiation of stomatal lineage cells. PMID: 24898766
9. Data indicate that H3K9 dimethylation level in mutants ros1 fpgs1 (folylpolyglutamate synthase 1) was clearly reduced. PMID: 23881414
10. the Arabidopsis RdDM pathway has an antisilencing function due to its role in maintaining ROS1 expression PMID: 22733760
11. The polalpha/incurvata2 (icu2) gene was isolated as one ros1 suppressor because its mutation leads to the reactivation of the silenced 35S-NPTII gene. PMID: 19769574
12. Data suggest that a function of REPRESSOR OF SILENCING 1 (ROS1) and DEMETER is to initiate erasure of 5-meC through a base excision repair process and provide strong biochemical evidence for the existence of an active DNA demethylation pathway in plants. PMID: 16624880
13. These results demonstrate that ROS1 is a 5-methylcytosine DNA glycosylase/lyase important for active DNA demethylation in Arabidopsis. PMID: 16864782
14. CpXpG and CpXpX sites become heavily methylated in the ros1 mutant. PMID: 17208187
15. ROS1 removes methylation that has multiple, independent origins, including de novo methylation directed by RDR2-dependent and -independent RNAi pathways. PMID: 17951456
16. Results suggest that ROS1 specificity arises by a combination of selective recognition at the active site and thermodynamic stability of the target base. PMID: 19443451

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KEGG: ath:AT2G36490

STRING: 3702.AT2G36490.1

UniGene: At.14091