ROS1

Proto-oncogene tyrosine-protein kinase ROS is a protein in humans that is encoded by ROS1 gene. Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.

Popular Product:

ROS1 Antibody (CSB-PA020072LA01HU)

Validated Data

Immunofluorescence staining of Hela cells with CSB-PA020072LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

The following ROS1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

ROS1 Antibodies

ROS1 Proteins

ROS1 Antibodies

ROS1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA185342	ROS1 Antibody	Human	ELISA,IHC
CSB-PA020072LA01HU	ROS1 Antibody	Human	ELISA, IF
CSB-PA020072LB01HU	ROS1 Antibody, HRP conjugated	Human	ELISA
CSB-PA020072LC01HU	ROS1 Antibody, FITC conjugated	Human
CSB-PA020072LD01HU	ROS1 Antibody, Biotin conjugated	Human	ELISA

ROS1 Antibodies for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Species Reactivity	Application
CSB-PA874445LA01DOA	ROS1 Antibody	Arabidopsis thaliana	ELISA
CSB-PA874445LB01DOA	ROS1 Antibody, HRP conjugated	Arabidopsis thaliana	ELISA
CSB-PA874445LC01DOA	ROS1 Antibody, FITC conjugated	Arabidopsis thaliana
CSB-PA874445LD01DOA	ROS1 Antibody, Biotin conjugated	Arabidopsis thaliana	ELISA

ROS1 Antibodies for Rattus norvegicus (Rat)

Code	Product Name	Species Reactivity	Application
CSB-PA737174XA01RA	Ros1 Antibody	Rattus norvegicus (Rat)	ELISA, WB (ensure identification of antigen)

ROS1 Antibodies for Gallus gallus (Chicken)

Code	Product Name	Species Reactivity	Application
CSB-PA020072XA01CH	ROS1 Antibody	Gallus gallus (Chicken)	ELISA, WB (ensure identification of antigen)

ROS1 Proteins

ROS1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP020072HU CSB-EP020072HU CSB-BP020072HU CSB-MP020072HU CSB-EP020072HU-B	Recombinant Human Proto-oncogene tyrosine-protein kinase ROS (ROS1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ROS1 Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP020072CH CSB-EP020072CH CSB-BP020072CH CSB-MP020072CH CSB-EP020072CH-B	Recombinant Chicken Proto-oncogene tyrosine-protein kinase ROS (ROS1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ROS1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP737174RA CSB-EP737174RA CSB-BP737174RA CSB-MP737174RA CSB-EP737174RA-B	Recombinant Rat Proto-oncogene tyrosine-protein kinase ROS (Ros1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ROS1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP755276MO CSB-EP755276MO CSB-BP755276MO CSB-MP755276MO CSB-EP755276MO-B	Recombinant Mouse Proto-oncogene tyrosine-protein kinase ROS (Ros1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ROS1 Proteins for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Source
CSB-YP874445DOA CSB-BP874445DOA CSB-MP874445DOA CSB-EP874445DOA-B	Recombinant Arabidopsis thaliana Protein ROS1 (ROS1), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP874445DOA	Recombinant Arabidopsis thaliana Protein ROS1 (ROS1), partial	E.coli

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